Biography
Dr. Jeshma Kovvuri received a Bachelor degree (B.Sc.) from the Kakatiya University, Warangal (2010), a Master of Science degree (M.Sc.) in Chemistry from Jawaharlal Nehru Technological University, Hyderabad, (2012), and her Ph.D. from CSIR-IICT, Hyderabad in 2018 under the supervision of Dr. Ahmed Kamal and C. G Ganesh Kumar, in the Division of Organic and Medicinal Chemistry. After working as an Assistant Professor at Vardhaman College of Engineering (Autonomous institution) for three years (2019-2022), she was appointed to the Department of Chemistry at Anurag University in 2022 as an Assistant Professor. She has good a number of publications in international peer reviewed journals, Participated in 11 FDP’s, 14 National and International conferences. She has also given 2 poster presentations and 1 oral presentation in conferences. She is a life member of CCN (ID. 60932221) and reviewer for Advanced Journal of Cancer Biology and Reviewer of Advanced Journal of Chemical Biology & Biologics.
Research Interests
Multi-disciplinary research programmes including organic synthesis, medicinal chemistry and photocatalysis. Design and synthesis of target-based new anticancer and antimicrobial agents, and their biological evaluation.
Teaching Interests
Dr. Jeshma Kovvuri has taught Applied, Engineering, Advanced Engineering and Materials Chemistry to Engineering students.
Selected Publications
- Phenstatin-based indole linked chalcone compound 9a exhibits antioral cancer activity by regulating NLRP3 inflammasome pathway. Jyoti Kode, Bhabani Jitendra Gour, Jeshma Kovvuri, Burri Nagaraju, Shailesh Jadhav, Madan Barkume, Pradip Chaudhari and Ahmed Kamal. Cancer Research, Manuscript Number: CAN-22-1876-2022.
- Development of New Molecular Entities as Potent Antifungal Agents: Synthesis of Substituted 1,2,3-Triazoles. A. Kishore, V. Sunitha, G. Ramesh and Jeshma Kovvuri. Russian Journal of General Chemistry, 91, 2546-2553, 2021.
- Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors. Jyoti Kode, Jeshma Kovvuri, Burri Nagaraju, Shailesh Jadhav, Madan Barkume, Pradip Chaudhari, Bhabani Jitendra Gour, Dilep C. G. Ganesh Kumar and Ahmed Kamal, Bioorganic Chemistry. 2020, December, 105, 104447.
- Visible Light Photoredox-Catalyzed Synthesis of Quinazolinone Derivatives and their cytotoxicity. Jeshma Kovvuri. Der Pharma Chemica, August, 2020, 12, 8- 1.
- Green synthesis of 1,2-dihydroquinazolinones and their cytotoxicity. Jeshma Kovvuri. Advanced Journal of Cancer Biology. March, 2020, 1, 1-9, ISSN 2319-5622.
- Amberlite IR-120H: Catalyzed synthesis of 1,3-diphenylpyrazole-chromenoquinolin-6-one compounds and their biological evaluation. Jeshma Kovvuri, Burri Nagaraju, C. Ganesh Kumar, Sunitha Rani Routhu, Jitendra Gour, Kishore Mullagiri, Narayana Nagesh and Ahmed Kamal. American Journal of Medicinal Chemistry, April 2020, 2(1), 2-16.
- Synthesis of Pyrazole Linked Benzothiazole-β-Naphthol Derivatives by Catalyst Free Method and Their Anticancer Evaluation. Jeshma Kovvuri, Burri Nagaraju, C. Ganesh Kumar, Sunitha Rani Routhu, Md. Adil Shareef, Manasa Kadagathur, Narayana Nagesh and Ahmed Kamal. Bioorg. Med. Chem. 2019, 27, 708-720.
- Design, Synthesis and Biological Evaluation of New β-Carboline-Bisindole Compounds as DNA Binding, Photocleavage Agents and Topoisomerase I Inhibitors. Jeshma Kovvuri, Burri Nagaraju, V. Lakshma Nayak, Ravikumar Akunuri, M. P. Narasimha Rao, Ayyappan Ajitha, Narayan Nagesh and Ahmed Kamal. Eur. J. Med. Chem., 2018, 143, 1563-1577.
- Synthesis of imidazo-thiadiazole linked indolinone conjugates and evaluated their microtubule network disrupting and apoptosis inducing ability. M. P. Narasimha Rao, Burri Nagaraju, Jeshma Kovvuri, Sowjanya Polepalli, Sateesh Alavala, M. V. P. S. Vishnuvardhan, P. Swapna, Vijaykumar D. Nimbarte, Jerripothula K. Lakshmi, Nishant Jain, Ahmed Kamal. Bioorg. Chem., 2018, 76, 420-436.
- Catalyst-free synthesis of pyrazole-aniline linked coumarin derivatives and their antimicrobial evaluation. Jeshma Kovvuri, Burri Nagaraju, C. Ganesh Kumar, K. Sirisha, Abdullah Alarifi, Ahmed Kamal. J. Saudi Chem. Soc., 2018, 22, 665-677.
- A facile one pot C-C and C-N bond formation for the synthesis of spiro-benzodiazepins and their cytotoxicity. Jeshma Kovvuri, Burri Nagaraju, K. Suresh Babu, Praveen Reddy Adiyala, Ahmed Kamal. Tetrahedron, 2017, 73, 6969-6976.
- Visible light diven coupling of 2-aminopyridines and α-ketovinylazides for the synthesis of imidazo[1,2-a]pyridines and their cytotoxicity. Praveen Reddy Adiyala, Kasinathuni Naga Visweswara Sastry, Jeshma Kovvuri, Apoorva Nagarajan, Ahmed Kamal. ChemistrySelect, 2017, 2, 8158-8161.
- Telomerase Inhibition and Human Telomeric G-Quadruplex DNA Stabilization by a β-Carboline−Benzimidazole Derivative at Low Concentrations. Kranthikumar Yadav, Penchala Narasimha Rao Meka, Sudeshna Sadhu, Sravanthi Devi Guggilapu, Jeshma Kovvuri, Ahmed Kamal, Ragampe Srinivas, Panuganti Devayani, Bathini Nagendra Babu, and Narayana Nagesh. ACS- Biochemistry, 2017, 56, 4392.
- An Efficient Synthesis of 2-Substituted Benzimidazoles via Photocatalytic Condensation of o-phenylenediamine and Aldehydes. Jeshma Kovvuri, Burri Nagaraju, Ahmed Kamal and Ajay K. Srivastava. ACS Comb.Sci., 2016, 18, 644.
- Amberlite IR-120H: an efficient and recyclable heterogeneous catalyst for the synthesis of pyrrolo[1, 2-a]quinoxalines and 5H-spiro[indoline-3,4-pyrrolo[1,2-a]quinoxali]-2-ones. Ahmed Kamal, Korrapati Suresh Babu, Jeshma Kovvuri, Vindravath Manasa, Abdullah Alarifi. Tetrahedron Lett., 2015, 56, 7012.
- Synthesis and Biological Evaluation of Imidazo[2,1-b][1,3,4]thiadiazole-Linked Oxindoles as Potent Tubulin Polymerization Inhibitors. Ahmed Kamal, M. P. Narasimha Rao, Pompi Das, Sowjanya Polepalli, Vijaykumar D. Nimbarte, Kishore Mullagiri, Jeshma Kovvuri and Nishant Jain. ChemMedChem., 2014, 9, 1463.
- Synthesis of β-carboline–benzimidazoles conjugates using lanthanum nitrate as a catalyst and their biological evaluation. Ahmed Kamal, Narasimha Rao, P. Swapna, Anver Basha Shaik, Jeshma Kovvuri, Vangala Santhosh Reddy, K. Vidyasagar and Narayana Nagesh. Org. Biomol. Chem., 2014, 12, 2370.
Selected Awards and Honors
- Awarded silver medal from Ministry of HRD for Soft Skills and Personality development.
- Awarded DST INSPIRE Fellowship.
- Senior Research Fellow at CSIR-IICT, Hyderabad.
- Junior Research Fellow at CSIR-IICT, Hyderabad.
- University Gold Medalist M.Sc. Chemistry Batch-2012, JNTUH.
External Profile Links
- 20013-2018- Doctor of Philosophy (Ph.D.) at CSIR-IICT, Hyderabad.
- 2010-2012- Master of Science (Drugs and Pharmaceutical Chemistry), JNTU-Hyderabad
- 2007-2010- Bachelor of Science (Chemistry, Microbiology and Biotechnology), Kakatiya University, Warangal, Telangana.
